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Interestingly, ursodeoxycholic acid, the only treatment approved by the Food and Drug Administration for the treatment of primary biliary cirrhosis, a chronic cholestatic disorder, was shown to prevent the fall in GCL expression during chronic cholestasis (Serviddio et al., 2004) and increase GCL expression in cultured rat hepatocytes (Mitsuyoshi et al., 1999)

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It is relevant the knowledge of the molecular mechanisms that guide and support fibrosis in endometriosis, to identify new drug targets and provide new therapeutic approaches to patients